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2-Bromothieno[3,2-C]Pyridin-4(5H)-One CAS NO 28948-60-9
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CAS No.:28948-60-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Bromothieno[3,2-C]Pyridin-4(5H)-One is a high-value brominated heterocyclic building block, essential for advanced organic synthesis and pharmaceutical research. Its unique fused thienopyridinone core, functionalized with a reactive bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.
Application
- Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
- Agrochemical Synthesis: Used in the creation of advanced active ingredients for crop protection products.
- Material Science Research: Serves as a precursor for the synthesis of organic electronic materials and functional dyes.
- Cross-Coupling Reactions: The bromine substituent enables pivotal metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for carbon-carbon bond formation.
- Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological evaluation.
- Academic & Institutional Research: A valuable reagent for methodological studies in synthetic organic chemistry and heterocyclic chemistry.
Basic Information
| Product Name | 2-Bromothieno[3,2-C]Pyridin-4(5H)-One |
| CAS No. | 28948-60-9 |
| Molecular Formula | C7H4BrNOS |
| Molecular Weight | 230.08 g/mol |
| Synonyms | 2-Bromothieno[3,2-c]pyridin-4(5H)-one; 4(5H)-Thieno[3,2-c]pyridinone, 2-bromo-; 2-Bromo-4,5-dihydrothieno[3,2-c]pyridin-4-one; 2-Bromo-5H-thieno[3,2-c]pyridin-4-one; 28948-60-9; AKOS005258065; BRN 1235435; CS-W009767; FT-0658081; NS00023827; SCHEMBL1552041 |
| EINECS | Contact for details |
Quality Control
Every batch of 2-Bromothieno[3,2-C]Pyridin-4(5H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with your specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light).
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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