Description

3,4-Dihydropyrrolo(3,2,1-Jk)(1,4)Benzodiazepin-1(2H)-One is a high-value, complex heterocyclic compound belonging to the benzodiazepine class, serving as a critical advanced intermediate in modern synthetic chemistry. Its fused tricyclic structure makes it a versatile and privileged scaffold for constructing novel pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on developing new central nervous system (CNS) agents, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel benzodiazepine analogs and other fused heterocyclic compounds with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a core scaffold in drug discovery programs targeting neurological disorders, anxiety, insomnia, and other CNS-related conditions.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides with novel modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Academic & Institutional R&D: A valuable compound for universities and research institutes conducting studies in organic synthesis methodology and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3,4-Dihydropyrrolo(3,2,1-Jk)(1,4)Benzodiazepin-1(2H)-One
CAS No.	28889-33-0
Molecular Formula	C12H10N2O
Molecular Weight	198.22 g/mol
Synonyms	1,2,3,4-Tetrahydropyrrolo[3,2,1-jk][1,4]benzodiazepin-1-one; Pyrrolo[3,2,1-jk][1,4]benzodiazepin-1(2H)-one, 3,4-dihydro-; 3,4-Dihydro-2H-pyrrolo[3,2,1-jk][1,4]benzodiazepin-1-one; 28889-33-0; Pyrrolobenzodiazepine tricyclic scaffold; Fused benzodiazepinone intermediate.
EINECS	Contact for details

Quality Control

Our 3,4-Dihydropyrrolo(3,2,1-Jk)(1,4)Benzodiazepin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements of research and development applications. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.