Description

[1,2,5-Trimethyl-4-Phenyl-5-(1-Piperidylmethyl)-4-Piperidyl] Propanoate Dihydrochloride is a high-purity, complex organic salt with the CAS number 28867-20-1. This compound is valued for its specific structural features, making it a critical advanced intermediate in sophisticated synthetic pathways. It is primarily sought by pharmaceutical research and development organizations and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel therapeutic compounds, particularly in central nervous system (CNS) and analgesic drug discovery.
• Chemical Research (R&D): Serves as a versatile precursor for developing new chemical entities (NCEs) and exploring structure-activity relationships (SAR) in medicinal chemistry.
• Fine Chemical Synthesis: Used in the production of complex, high-value specialty chemicals requiring a specific piperidine-based structural motif.
• Reference Standard: Supplied as a high-purity analytical standard for quality control, method development, and regulatory submissions in pharmaceutical analysis.
• Academic Research: Employed in university and institutional laboratories for studies in organic synthesis, pharmacology, and chemical biology.

Basic Information

Product Name	[1,2,5-Trimethyl-4-Phenyl-5-(1-Piperidylmethyl)-4-Piperidyl] Propanoate Dihydrochloride
CAS No.	28867-20-1
Molecular Formula	C24H38N2O2 · 2HCl
Molecular Weight	467.49 g/mol (Free base: 386.57 g/mol)
Synonyms	1,2,5-Trimethyl-4-phenyl-5-(1-piperidylmethyl)-4-piperidinol propionate dihydrochloride; 4-Piperidinol, 1,2,5-trimethyl-4-phenyl-5-(1-piperidinylmethyl)-, propanoate (ester), dihydrochloride; Propanoic acid, 1,2,5-trimethyl-4-phenyl-5-(1-piperidinylmethyl)-4-piperidinyl ester, dihydrochloride; 3-(1,2,5-Trimethyl-4-phenyl-5-piperidin-1-ylmethyl-piperidin-4-yloxy)-propionic acid dihydrochloride
EINECS	Contact for details

Quality Control

Our [1,2,5-Trimethyl-4-Phenyl-5-(1-Piperidylmethyl)-4-Piperidyl] Propanoate Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research and pharmaceutical applications. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.