Description

1-Chloro-2,2,2-Trifluoroethyl Radical is a highly reactive organofluorine intermediate of significant interest in advanced chemical synthesis. Its unique structure, featuring a chlorine atom and three fluorine atoms on a single carbon, makes it a valuable building block for introducing the trifluoroethyl group into complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where fluorination can enhance activity and environmental persistence profiles.
• Material Science Research: Acts as a precursor for developing novel fluorinated polymers, coatings, and liquid crystals with specialized properties like chemical resistance and low surface energy.
• Organic Synthesis Reagent: Employed in radical reactions and other synthetic methodologies to construct complex, fluorinated organic compounds in academic and industrial R&D settings.
• Fluorine Chemistry Studies: Essential for fundamental research into the behavior and reactivity of polyhalogenated alkyl radicals.

Basic Information

Product Name	1-Chloro-2,2,2-Trifluoroethyl Radical
CAS No.	28760-99-8
Molecular Formula	C2HClF3•
Molecular Weight	132.48 g/mol
Synonyms	1-Chloro-2,2,2-trifluoroethyl; 2-Chloro-1,1,1-trifluoroethyl Radical; Trifluorochloroethyl Radical; (Chlorotrifluoroethyl) Radical; CF3CHCl•; α-Chloro-α,α,α-trifluoroethyl Radical; 2,2,2-Trifluoro-1-chloroethyl Radical; 1-Chloro-2,2,2-trifluoroethane Radical
EINECS	Contact for details

Quality Control

Our production of high-purity chemical intermediates adheres to stringent internal quality protocols. Each batch of 1-Chloro-2,2,2-Trifluoroethyl Radical is characterized using advanced analytical techniques to confirm identity and assess purity. A comprehensive Certificate of Analysis (COA) detailing specific batch results is provided with every shipment to ensure traceability and support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and reactive radical nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures, typically between -20°C to -80°C for long-term stability. Store away from strong acids, oxidizers, and other incompatible materials in a dedicated, well-ventilated area.

Specification

Item	Specification
Appearance	Contact for details
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical)
Volatile Impurities (GC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.