Description

2,3,4,9-Tetrahydro-6-Methoxy-1-(3-Pyridinyl)-1H-Pyrido(3,4-B)Indole Hydrochloride is a high-purity, complex heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its intricate molecular structure makes it a valuable intermediate for synthesizing novel therapeutic agents targeting the central nervous system. This compound is essential for research chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality chemical intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
• Biochemical Research: Used as a reference standard or probe in studies investigating receptor binding, enzyme inhibition, and other molecular interactions.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of complex active pharmaceutical ingredients (APIs).
• Academic Research: Serves as a starting material for novel heterocyclic chemistry and methodology development in university and institutional laboratories.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage pharmaceutical development services.

Basic Information

Item	Details
Product Name	2,3,4,9-Tetrahydro-6-Methoxy-1-(3-Pyridinyl)-1H-Pyrido(3,4-B)Indole Hydrochloride
CAS No.	28717-19-3
Molecular Formula	C18H19N3O • HCl
Molecular Weight	329.82 g/mol (Free base: 293.37 g/mol)
Synonyms	6-Methoxy-1-(3-pyridinyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride; 1-(3-Pyridinyl)-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride; Tetrahydroharmine hydrochloride (partial); 28717-19-3; 6-MeO-THPi HCl; Pyridoindole derivative hydrochloride
EINECS	Contact for details

Quality Control

Every batch of our 2,3,4,9-Tetrahydro-6-Methoxy-1-(3-Pyridinyl)-1H-Pyrido(3,4-B)Indole Hydrochloride is manufactured and tested under a strict quality management system. We ensure compliance with ICH guidelines for impurities and provide comprehensive analytical data. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.