Description

Isoxazolo[3,4-D]Pyrimidine (8Ci,9Ci) is a high-purity, fused heterocyclic compound with the CAS registry number 28648-19-3, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique bicyclic scaffold, incorporating both isoxazole and pyrimidine rings, provides a versatile building block for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic reactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems and enzyme activity.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs.
• Custom Synthesis & Scale-Up: Available for custom manufacturing projects, from gram-scale research to multi-kilogram commercial production.

Basic Information

Product Name	Isoxazolo[3,4-D]Pyrimidine (8Ci,9Ci)
CAS No.	28648-19-3
Molecular Formula	C5H3N3O
Molecular Weight	121.10 g/mol
Synonyms	Isoxazolo[3,4-d]pyrimidine; 1H-Isoxazolo[3,4-d]pyrimidine; Isoxazolo(3,4-d)pyrimidine; 28648-19-3; Isoxazolopyrimidine; NSC 169060; AI3-52298; CCRIS 6661
EINECS	Contact for details

Quality Control

Every batch of Isoxazolo[3,4-D]Pyrimidine (8Ci,9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for advanced research and commercial applications. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.