Description

Bicyclo[2.2.1]Heptan-2-Ol, Methanesulfonate, (1R,2S,4S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its rigid bicyclic framework and functional handles, which are crucial for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in enantioselective transformations.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Heptan-2-Ol, Methanesulfonate, (1R,2S,4S)-Rel- (9Ci)
CAS No.	28627-78-3
Molecular Formula	C9H16O4S
Molecular Weight	220.29 g/mol
Synonyms	(1R,2S,4S)-(-)-2-Norbornyl Methanesulfonate; (1R,2S,4S)-(-)-Bicyclo[2.2.1]heptan-2-yl methanesulfonate; (-)-endo-2-Norbornyl Methanesulfonate; endo-(-)-2-Norbornanol Methanesulfonate; (1R,2S,4S)-rel-2-Bicyclo[2.2.1]heptanyl methanesulfonate; endo-2-Norbornyl mesylate; (-)-2-Norbornyl mesylate
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, Chiral HPLC, and NMR to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.