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Bicyclo[2.2.1]Heptan-2-Ol, Methanesulfonate, (1R,2R,4S)-Rel- (9Ci) CAS NO 28627-77-2


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CAS No.:28627-77-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bicyclo[2.2.1]Heptan-2-Ol, Methanesulfonate, (1R,2R,4S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block and synthetic intermediate. This compound is valued for its rigid bicyclic framework and functional handles, which are critical for constructing complex molecular architectures with precise three-dimensional control. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active pharmaceutical ingredients (APIs).

Application

  • Chiral Intermediate in Pharmaceutical Synthesis: Serves as a key precursor for the development of enantiomerically pure drugs, particularly those targeting the central nervous system or requiring specific steric profiles.
  • Asymmetric Catalysis & Ligand Design: Used in the research and preparation of novel chiral ligands and catalysts for stereoselective transformations.
  • Advanced Material Research: Acts as a monomer or functional modifier in the synthesis of specialty polymers with unique thermal or mechanical properties.
  • Agrochemical Intermediate: Employed in the synthesis of chiral active ingredients for crop protection agents.
  • Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new reaction pathways.
  • Flavor & Fragrance Ingredient Synthesis: Utilized as a building block for creating complex, naturally-derived odorants and flavor compounds.

Basic Information

Item Details
Product Name Bicyclo[2.2.1]Heptan-2-Ol, Methanesulfonate, (1R,2R,4S)-Rel- (9Ci)
CAS No. 28627-77-2
Molecular Formula C8H14O4S
Molecular Weight 206.26 g/mol
Synonyms (1R,2R,4S)-Bicyclo[2.2.1]heptan-2-yl methanesulfonate; (1R,2R,4S)-2-Norbornyl methanesulfonate; endo-(1R,2R,4S)-2-Norbornanol methanesulfonate; rel-(1R,2R,4S)-Bicyclo[2.2.1]hept-2-yl methanesulfonate; endo-Norborneol methanesulfonate (stereospecific); Bicyclo[2.2.1]heptan-2-ol, methanesulfonate, (1R-endo)-; (1R,2R,4S)-rel-2-Norbornyl mesylate
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Quality Control

Our Bicyclo[2.2.1]Heptan-2-Ol, Methanesulfonate, (1R,2R,4S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline solid or powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee (enantiomeric excess)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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