Description

2-(1-Chloro-Ethyl)-Thiophene is a versatile organosulfur building block characterized by its reactive chloroethyl side chain attached to a thiophene heterocycle. This compound is crucial for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate. It is primarily sought by R&D chemists and process development teams in fine chemical, pharmaceutical, and advanced material industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a monomer or building block for conducting polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis in cross-coupling and other organic transformations.
• Fine Chemical Production: Acts as an intermediate for dyes, pigments, and other specialty chemicals requiring the thiophene scaffold.

Basic Information

Product Name	2-(1-Chloro-Ethyl)-Thiophene
CAS No.	28612-98-8
Molecular Formula	C6H7ClS
Molecular Weight	146.64 g/mol
Synonyms	1-(2-Thienyl)-1-chloroethane; 1-Chloro-1-(2-thienyl)ethane; 2-(1-Chloroethyl)thiophene; α-Chloroethylthiophene; 2-Thienylchloroethane; 2-(Chloroethyl)thiophene (isomeric); Thiophene, 2-(1-chloroethyl)-; 28612-98-8
EINECS	Contact for details

Quality Control

Our 2-(1-Chloro-Ethyl)-Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting precise specifications are available for each lot upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.