Description

1,2-Diazabicyclo[3.3.1]Nonane is a versatile bicyclic amidine base and catalyst with a unique sterically hindered structure. This compound matters for its exceptional performance as a non-nucleophilic, strong organic base in demanding synthetic transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high selectivity and minimal side reactions.

Application

• Pharmaceutical Synthesis: As a catalyst in the synthesis of active pharmaceutical ingredients (APIs), particularly for reactions sensitive to nucleophilic attack.
• Polymer Chemistry: Serving as a catalyst or initiator in the production of specialized polymers, including polyurethanes and polyamides.
• Asymmetric Catalysis: Utilized as a chiral base or ligand precursor in enantioselective synthesis to create optically pure compounds.
• Organic Methodology Development: A key reagent in novel bond-forming reactions, such as amidinations and guanylation reactions.
• Agrochemical Manufacturing: Employed in the synthesis of advanced herbicides, fungicides, and insecticides where precise molecular architecture is critical.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new reaction pathways and mechanistic studies.

Basic Information

Product Name	1,2-Diazabicyclo[3.3.1]Nonane
CAS No.	28579-90-0
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	1,2-Diazabicyclo[3.3.1]nonane; DBN (common abbreviation); 2,3,4,6,7,8-Hexahydro-1H-pyrimido[1,2-a]pyrimidine; 1,5-Diazabicyclo[3.3.1]non-5-ene (tautomer); Amidino Piperidine Derivative; Bicyclic Amidine Base; DBU Analog (structural analog); Strong Organic Base Catalyst
EINECS	Contact for details

Quality Control

Our 1,2-Diazabicyclo[3.3.1]Nonane is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and performance. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.