Description

Methanol (D2) CAS NO 28563-35-1 is a deuterated isotopologue of methanol, where the hydrogen atoms are replaced by deuterium (²H or D), a stable, non-radioactive isotope. This isotopic labeling is critical for applications requiring precise molecular tracking and reduced signal interference. It is an essential reagent for advanced research and analytical techniques in pharmaceutical development, materials science, and nuclear magnetic resonance (NMR) spectroscopy.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for proton NMR, providing a non-interfering lock signal and background for analyzing organic compounds.
• Pharmaceutical Research & Development: Serves as a labeled precursor or solvent in the synthesis and metabolic studies of deuterated drug candidates to enhance pharmacokinetic properties.
• Mechanistic & Kinetic Studies: Employed as a tracer in chemical reaction mechanisms and kinetic isotope effect (KIE) studies to elucidate reaction pathways.
• Mass Spectrometry & Analytical Standards: Used in the preparation of internal standards for quantitative LC-MS and GC-MS analysis to ensure accuracy and reproducibility.
• Organic Synthesis: Acts as a deuterium source or deuterated reagent in synthetic chemistry for introducing stable isotopes into target molecules.
• Polymer & Materials Science: Utilized in the research of deuterated polymers and materials for neutron scattering experiments and structural analysis.

Basic Information

Product Name	Methanol (D2)
CAS No.	28563-35-1
Molecular Formula	CD₄O
Molecular Weight	36.07 g/mol
Synonyms	Deuterated Methanol; Methanol-d4; Tetradeuteromethanol; Deuteromethanol; [²H₄]Methanol; Perdeuterated Methanol; CD₃OD; Methyl Alcohol-d4
EINECS	Contact for details

Quality Control

Our Methanol (D2) is produced and handled under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR spectroscopy and gas chromatography, to verify isotopic purity (D-enrichment ≥ 99.8 atom % D) and chemical purity. A detailed Certificate of Analysis (COA) is provided, confirming compliance with our rigorous internal specifications and suitability for sensitive spectroscopic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). This product is highly volatile and hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent absorption of atmospheric moisture and to minimize evaporation.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Isotopic Purity (NMR)	≥ 99.8 atom % D
Chemical Purity (GC)	≥ 99.9%
Water Content (KF)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.