Description

α-Diazo-β-Oxobenzenepropionic Acid Ethyl Ester is a specialized diazo carbonyl compound that serves as a versatile building block in advanced organic synthesis. Its unique molecular structure, featuring both a diazo and a β-keto ester group, makes it a valuable precursor for generating reactive carbene intermediates. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic frameworks and for use in cyclopropanation and C-H insertion reactions.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex bioactive molecules, including potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its reactivity to create new chemical entities.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cyclopropanation reactions, ring expansions, and the synthesis of strained carbocycles.
• Material Science Precursor: Investigated for the preparation of specialized polymers and functional materials that require precise molecular architectures.
• Catalyst and Ligand Development: Serves as a starting material for creating novel metal-organic complexes and catalysts.

Basic Information

Product Name	α-Diazo-β-Oxobenzenepropionic Acid Ethyl Ester
CAS No.	28383-65-5
Molecular Formula	C₁₁H₁₀N₂O₃
Molecular Weight	218.21 g/mol
Synonyms	Ethyl 2-Diazo-3-oxo-3-phenylpropionate; Ethyl 2-Diazo-3-oxo-3-phenylpropanoate; 2-Diazo-3-oxo-3-phenylpropionic Acid Ethyl Ester; α-Diazo-β-oxo-benzenepropanoic Acid Ethyl Ester; Ethyl α-Diazo-β-oxohydrocinnamate; NSC 334365; Ethyl (Diazo)(oxo)(phenyl)acetate; Ethyl Diazobenzoylacetate
EINECS	Contact for details

Quality Control

Every batch of α-Diazo-β-Oxobenzenepropionic Acid Ethyl Ester is produced and tested under strict quality management protocols to ensure high purity and consistency. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in the dark, such as in amber glass or an opaque secondary container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.