Description

(1β)-4α,7,7-Trimethylbicyclo[2.2.1]Heptane-2β,3α-Diol CAS NO 28357-12-2 is a high-purity bicyclic diol derivative, valued for its unique stereochemistry and functional groups which make it a versatile chiral building block and intermediate in advanced organic synthesis. This compound is critical for ensuring precise molecular architecture in the production of complex, high-value specialty chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing active ingredients, ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its rigid bicyclic structure contributes to biological activity and environmental stability.
• Fine Chemical & Specialty Chemical Production: Acts as a building block for fragrances, flavors, and performance chemicals requiring specific stereochemical configurations.
• Catalyst & Ligand Development: Utilized in the design and synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Polymer Science: Employed as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal or mechanical properties.
• Academic & Industrial Research: A valuable compound for methodological development in organic chemistry and material science research.

Basic Information

Product Name	(1β)-4α,7,7-Trimethylbicyclo[2.2.1]Heptane-2β,3α-Diol
CAS No.	28357-12-2
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	2,3-Dihydroxy-1,7,7-trimethylnorbornane; 1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-diol; 2,3-Dihydroxybornane; 2,3-Dihydroxycamphane; (1S,2R,3S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-diol; endo-Bornane-2,3-diol; (1R,2S,3R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-diol
EINECS	Contact for details

Quality Control

Our (1β)-4α,7,7-Trimethylbicyclo[2.2.1]Heptane-2β,3α-Diol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high purity and consistent stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.