Description

1,3,5-Triphenylcyclohexane-D5 is a deuterated isotopologue of 1,3,5-triphenylcyclohexane, where five hydrogen atoms are replaced with deuterium. This compound is a crucial analytical standard and internal reference material, providing enhanced mass spectrometry and NMR signal resolution for precise quantitative analysis. It is primarily required by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and advanced materials sectors for method development, metabolic studies, and trace-level impurity profiling.

Application

• Internal Standard for GC-MS and LC-MS analysis in pharmacokinetic and metabolomic studies.
• Deuterated NMR solvent shift reagent and quantitative NMR (qNMR) standard for structural elucidation.
• Isotope dilution mass spectrometry (IDMS) reference material for achieving high-accuracy quantification in complex matrices.
• Critical component in the synthesis of deuterium-labeled pharmaceutical intermediates and active ingredients.
• Stable isotope tracer in environmental fate studies and degradation pathway analysis for agrochemicals.
• Calibration standard for analytical instrument validation and method qualification in GLP/GMP environments.
• Research chemical for studying reaction mechanisms and kinetic isotope effects (KIE) in organic synthesis.

Basic Information

Product Name	1,3,5-Triphenylcyclohexane-D5
CAS No.	28336-57-4
Molecular Formula	C24H19D5
Molecular Weight	323.49 g/mol
Synonyms	1,3,5-Tris(phenyl)cyclohexane-d5; [D5]-1,3,5-Triphenylcyclohexane; 1,3,5-Triphenylcyclohexane (phenyl-d5); Cyclohexane, 1,3,5-triphenyl-, deuterated; Deuterated 1,3,5-Triphenylcyclohexane; Isotopic Labeled 1,3,5-TPC; 1,3,5-TPC-d5
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced and tested under stringent quality systems to ensure isotopic purity and chemical integrity, essential for reliable analytical results. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-content), chemical purity, and confirming identity via spectroscopic methods. We support compliance with ISO, GMP, and ICH Q2(R2) guidelines for analytical procedure validation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.