Description

4-Methylphenyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-B-D-Glucopyranoside is a high-purity, protected thioglycoside building block essential for synthetic carbohydrate chemistry. This compound serves as a critical intermediate for the controlled synthesis of complex oligosaccharides and glycoconjugates, enabling precise glycosidic bond formation. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic tools, and biochemical probes.

Application

• Glycoscience Research: A fundamental building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the development of carbohydrate-based drugs, including antiviral agents, antibiotics, and cancer therapeutics.
• Glycoconjugate Synthesis: Key precursor for creating glycoproteins, glycolipids, and neoglycoconjugates for biological studies.
• Chemical Biology Probes: Enables the creation of labeled or modified sugars to study carbohydrate-protein interactions and metabolic pathways.
• Enzyme Substrate Development: Serves as a substrate or inhibitor in assays for glycosidase and glycosyltransferase enzymes.
• Material Science: Potential monomer for synthesizing novel carbohydrate-based polymers and smart materials.

Basic Information

Product Name	4-Methylphenyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-B-D-Glucopyranoside
CAS No.	28244-94-2
Molecular Formula	C21H26O9S
Molecular Weight	454.49 g/mol
Synonyms	p-Tolyl 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranoside; 1-Thio-β-D-glucopyranoside, 4-methylphenyl 2,3,4,6-tetraacetate; 4-Methylphenyl 1-Thio-β-D-glucopyranoside Tetraacetate; p-Tolyl 1-Thio-β-D-glucopyranoside Tetraacetate; Thioglucoside Tetraacetate; Acetylated Thioglucopyranoside; Glycosyl Donor Building Block
EINECS	Contact for details

Quality Control

Our 4-Methylphenyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-B-D-Glucopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.