Description

Acetophenone-2',3',4',5',6'-D5 is a deuterium-labeled isotopologue of acetophenone, a key aromatic ketone, where five hydrogen atoms on the phenyl ring are replaced with deuterium (D). This compound is essential as a stable isotope-labeled internal standard for precise quantitative analysis in mass spectrometry, eliminating interference from the unlabeled analyte. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing industries to ensure accurate measurement of acetophenone and related metabolites or impurities.

Application

• Internal Standard for Mass Spectrometry (MS): Critical for quantitative LC-MS/MS and GC-MS analysis in pharmacokinetic and metabolomic studies.
• Pharmaceutical Research & Development: Used in the analysis of drug substances, metabolites, and degradation products to meet regulatory requirements for method validation.
• Environmental Analysis: Enables accurate tracing and quantification of acetophenone as an environmental pollutant or industrial byproduct.
• Agrochemical Testing: Serves as a reference standard in the analysis of pesticides and their breakdown products.
• Chemical Synthesis Research: Acts as a labeled starting material or tracer in reaction mechanism studies and synthetic chemistry.
• Forensic Toxicology: Supports the accurate identification and quantification of substances in complex biological matrices.

Basic Information

Product Name	Acetophenone-2',3',4',5',6'-D5
CAS No.	28077-64-7
Molecular Formula	C8H3D5O
Molecular Weight	125.19 g/mol
Synonyms	Deuteroacetophenone-d5; Acetophenone-phenyl-d5; Methyl phenyl ketone-d5; 1-Phenylethanone-2,3,4,5,6-d5; Benzoylmethane-d5; (Deuterophenyl)methyl ketone; Acetophenone (ring-d5); NSC 7636-d5
EINECS	Contact for details

Quality Control

Every batch of Acetophenone-2',3',4',5',6'-D5 is produced and tested under strict quality management systems to ensure the highest isotopic and chemical purity for analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on isotopic enrichment, chemical purity, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.