Description

(1S)-1-(Thiophen-2-Yl)Ethan-1-Amine CAS NO 27948-34-1 is a high-purity chiral amine building block featuring a thiophene heterocycle. This compound is of significant value in asymmetric synthesis and pharmaceutical research due to its role as a key intermediate for creating molecules with specific three-dimensional structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides, where stereochemistry impacts biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands used in asymmetric catalysis, such as for hydrogenation or cross-coupling reactions.
• Organic Electronic Materials: Acts as a building block for novel conjugated molecules and polymers in OLED and semiconductor research, leveraging the thiophene moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring enantiomerically pure amines with heterocyclic components.

Basic Information

Product Name	(1S)-1-(Thiophen-2-Yl)Ethan-1-Amine
CAS No.	27948-34-1
Molecular Formula	C6H9NS
Molecular Weight	127.21 g/mol
Synonyms	(S)-1-(2-Thienyl)ethylamine; (S)-(-)-1-(2-Thienyl)ethylamine; (S)-α-Methyl-2-thiophenemethylamine; (1S)-1-(Thiophen-2-yl)ethanamine; (S)-1-(Thiophen-2-yl)ethan-1-amine; (S)-2-(1-Aminoethyl)thiophene; (S)-1-(2-Thienyl)ethanamine
EINECS	Contact for details

Quality Control

Our (1S)-1-(Thiophen-2-Yl)Ethan-1-Amine is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, to confirm identity, purity, and optical rotation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.