Description

6-Sulfanylnicotinonitrile is a versatile sulfur-containing heterocyclic building block with significant synthetic utility. Its core value lies in its bifunctional structure, featuring both a reactive thiol group and a cyano-substituted pyridine ring, enabling its use in the construction of complex molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing cyano group.
• Chemical Biology Probes: Utilized for designing activity-based probes and bioconjugation agents that target thiol-reactive sites in proteins.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	6-Sulfanylnicotinonitrile
CAS No.	27885-58-1
Molecular Formula	C6H4N2S
Molecular Weight	136.17 g/mol
Synonyms	6-Mercaptonicotinonitrile; 6-Thionicotinonitrile; 3-Cyano-2-pyridinethiol; 2-Pyridinethiol-3-carbonitrile; 6-Sulfanylpyridine-3-carbonitrile; 6-Mercapto-3-cyanopyridine; 3-Cyano-2-mercaptopyridine; 6-Thiolnicotinonitrile
EINECS	Contact for details

Quality Control

Our 6-Sulfanylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. This product is easily oxidized and light-sensitive. Keep away from strong oxidizing agents and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.