Description

2-Bromo-6,7-Dihydro-1H-Indol-4(5H)-One is a versatile brominated indolinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex heterocyclic systems, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening due to its reactive bromine and ketone functionalities.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules, dyes, and functional materials.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-6,7-Dihydro-1H-Indol-4(5H)-One
CAS No.	27784-79-8
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	2-Bromo-4,5,6,7-tetrahydro-1H-indol-4-one; 2-Bromo-4-oxo-4,5,6,7-tetrahydro-1H-indole; 2-Bromo-1,4,5,6,7,7a-hexahydro-4-oxoindole; 2-Bromotetrahydroindol-4-one; 2-Bromo-6,7-dihydro-1H-indol-4(5H)-one; 2-Bromo-4,5,6,7-tetrahydroindol-4-one
EINECS	Contact for details

Quality Control

Our 2-Bromo-6,7-Dihydro-1H-Indol-4(5H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.