Description

m-(Trimethylsilyloxy)Phenylacetic Acid Trimethylsilyl Ester is a versatile organosilicon-protected derivative of phenylacetic acid. This compound is a critical synthetic intermediate, valued for its role in protecting sensitive functional groups during complex organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the production of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protection of carboxylic acid groups.
• Peptide Synthesis: Used as a protected synthon in the preparation of non-natural amino acids and complex peptide fragments.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Synthesis: Employed in the creation of advanced organic electronic materials and display components.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Heck couplings for constructing biaryl systems.
• Chemical Derivatization: Used in analytical chemistry to prepare volatile derivatives for Gas Chromatography (GC) or GC-Mass Spectrometry (GC-MS) analysis.

Basic Information

Product Name	m-(Trimethylsilyloxy)Phenylacetic Acid Trimethylsilyl Ester
CAS No.	27750-55-6
Molecular Formula	C14H24O3Si2
Molecular Weight	296.51 g/mol
Synonyms	3-(Trimethylsilyloxy)phenylacetic Acid Trimethylsilyl Ester; m-(Trimethylsiloxy)phenylacetic Acid Trimethylsilyl Ester; [3-(Trimethylsilyloxy)phenyl]acetic Acid Trimethylsilyl Ester; Phenylacetic Acid, 3-(Trimethylsilyloxy)-, Trimethylsilyl Ester; Trimethylsilyl 3-(Trimethylsilyloxy)phenylacetate; TMS-protected 3-Hydroxyphenylacetic Acid
EINECS	Contact for details

Quality Control

Our m-(Trimethylsilyloxy)Phenylacetic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.