Description

4-(3-tert-Butylamino-2-Hydroxypropoxy)-2-Carboxyindole is a key indole-based chemical intermediate with a complex molecular structure featuring both carboxylic acid and amino alcohol functionalities. This compound is valued for its role in the synthesis of more complex active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of potential β-adrenergic blocking agents (β-blockers) and other cardiovascular drugs.
• Agrochemical Research: Used in the development of new herbicides and plant growth regulators, leveraging its indole core structure.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in organic chemistry laboratories and pilot-scale production.
• Biochemical Research: Employed in studies investigating receptor-ligand interactions due to its structural similarity to certain bioactive indole alkaloids.
• Material Science: Potential monomer or additive in the development of specialized polymers with unique properties.

Basic Information

Product Name	4-(3-tert-Butylamino-2-Hydroxypropoxy)-2-Carboxyindole
CAS No.	27748-04-5
Molecular Formula	C₁₆H₂₂N₂O₄
Molecular Weight	306.36 g/mol
Synonyms	2-Carboxy-4-(3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy)-1H-indole; 4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid; Carazolol Carboxylic Acid; Carazolol Impurity C; Carazolol Related Compound C; 27748-04-5; 4-(3-tert-Butylamino-2-hydroxypropoxy)-2-indolecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-(3-tert-Butylamino-2-Hydroxypropoxy)-2-Carboxyindole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide detailed Certificates of Analysis (COA) with each shipment, ensuring full traceability and compliance with customer specifications for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.