Description

n-Tosylphthalimide is a versatile organic synthesis intermediate, primarily valued for its role as a tosylating and protecting agent. Its significance lies in its ability to introduce the robust tosyl (p-toluenesulfonyl) group into target molecules, facilitating a wide range of chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used in the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and advanced materials.

Application

• Pharmaceutical Synthesis: Key intermediate in the production of active pharmaceutical ingredients (APIs), particularly as a protecting group for amines and alcohols.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a reagent for the selective tosylation of amino acids during peptide synthesis.
• Polymer & Material Science: Acts as a monomer or modifying agent in the creation of specialty polymers, resins, and functional materials.
• Organic Synthesis Research: A fundamental reagent in academic and industrial R&D for constructing complex molecular architectures.
• Dye & Pigment Industry: Intermediate in the synthesis of certain high-performance dyes and organic pigments.

Basic Information

Product Name	n-Tosylphthalimide
CAS No.	27722-45-8
Molecular Formula	C15H13NO4S
Molecular Weight	303.33 g/mol
Synonyms	N-(p-Toluenesulfonyl)phthalimide; p-Toluenesulfonylphthalimide; Tosylphthalimide; Phthalimide, N-(p-toluenesulfonyl)-; 1H-Isoindole-1,3(2H)-dione, 2-[(4-methylphenyl)sulfonyl]-; N-Tosylphthalimide; N-p-Toluenesulfonylphthalimide; TsPhth
EINECS	Contact for details

Quality Control

Our n-Tosylphthalimide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	168 - 172 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.