Description

1-Azabicyclo(2.2.2)Octane, 4-Iodo- is a versatile and highly functionalized bicyclic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique quinuclidine core with an iodine substituent makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for chemists and researchers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for drug discovery, catalyst development, and material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and anti-infective agents.
• Ligand Synthesis: Used to create sophisticated ligands for catalysis, including transition metal catalysts for asymmetric synthesis.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes to study enzyme function and receptor interactions.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for functional polymers and advanced organic materials with specific electronic or structural properties.
• Cross-Coupling Reactions: The iodine atom facilitates participation in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.

Basic Information

Item	Details
Product Name	1-Azabicyclo(2.2.2)Octane, 4-Iodo-
CAS No.	27701-90-2
Molecular Formula	C7H12IN
Molecular Weight	237.08 g/mol
Synonyms	4-Iodoquinuclidine; 4-Iodo-1-azabicyclo[2.2.2]octane; Quinuclidine, 4-iodo-; 1-Azabicyclo[2.2.2]octane, 4-iodo-; 4-Iodo-1-azoniabicyclo[2.2.2]octane; 4-Iodo-1-azabicyclo(2.2.2)octane; 4-Iodoquinuclidinium
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo(2.2.2)Octane, 4-Iodo- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.