Description

Ethyl Acetate, [1-14C] is a carbon-14 labeled isotopologue of the common organic solvent ethyl acetate, specifically labeled at the carbonyl carbon position. This product is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies where tracking the molecule's pathway is required. It is a critical reagent for researchers and scientists in the pharmaceutical, agrochemical, and environmental science industries who require high-specific-activity radiolabeled tracers for advanced analytical applications.

Application

• Radiolabeled Tracer Studies: Used as a labeled precursor or solvent in metabolic and pharmacokinetic research to track the absorption, distribution, metabolism, and excretion (ADME) of compounds.
• Pharmaceutical Development: Employed in the synthesis and analysis of radiolabeled drug candidates for regulatory submission and mechanistic studies.
• Environmental Fate Analysis: Applied in studies to understand the degradation pathways, persistence, and breakdown products of chemicals in ecosystems.
• Biochemical Research: Serves as a volatile extraction solvent or reagent in procedures requiring isotopic labeling for detection by liquid scintillation counting (LSC) or accelerator mass spectrometry (AMS).
• Chemical Synthesis Intermediate: Acts as a radiolabeled building block for the synthesis of more complex 14C-labeled organic molecules.
• Quality Control & Analytical Method Development: Used as an internal standard or reference material in developing highly sensitive analytical methods like HPLC-radiochemical detection.

Basic Information

Product Name	Ethyl Acetate, [1-14C]
CAS No.	27569-23-9
Molecular Formula	C4H814CO2 or CH314COOC2H5
Molecular Weight	~89.10 g/mol (exact mass depends on specific activity)
Synonyms	Acetic-1-14C Acid Ethyl Ester; Ethyl Acetate-1-14C; [1-14C]Ethyl Acetate; Ethyl (1-14C)acetate; Acetic-1-14C Acid Ethyl Ester; Ethyl Ethanoate-1-14C; 14C-Ethyl Acetate (Carbonyl Labeled)
EINECS	Contact for details

Quality Control

Every batch of Ethyl Acetate, [1-14C] is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Certificates of Analysis (COA) are provided, detailing key parameters such as radiochemical purity (by HPLC), chemical purity, specific activity, and solvent composition. Our production adheres to relevant guidelines for the handling of radioactive materials, ensuring reliable and consistent performance for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, well-ventilated area for radioactive materials. Due to its highly volatile nature, ensure containers are securely sealed to prevent evaporation and potential contamination. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (GC)	≥ 99%
Specific Activity	50-60 mCi/mmol (Custom ranges available)
Solvent	Ethyl Acetate (or as specified)
Concentration	1.0 mCi/mL (Custom concentrations available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.