Description

1,1-Difluorocycloheptane is a versatile fluorinated organic building block characterized by its unique seven-membered ring structure. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for introducing difluoromethylene groups into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluoromethylene group can improve biological activity and environmental persistence.
• Material Science Precursor: Acts as a monomer or modifying agent in the synthesis of specialty polymers and fluorinated materials with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Employed in academic and industrial research for cyclopropanation reactions, ring-expansion studies, and the construction of complex, fluorinated carbo- and heterocycles.
• Liquid Crystal & Electronic Chemicals: Investigated for use in the formulation of fluorinated liquid crystals and dielectric fluids for electronic applications.

Basic Information

Product Name	1,1-Difluorocycloheptane
CAS No.	27371-42-2
Molecular Formula	C7H12F2
Molecular Weight	134.17 g/mol
Synonyms	Cycloheptane, 1,1-difluoro-; 1,1-Difluorocycloheptane; Difluorocycloheptane; 1,1-Difluoroheptamethylene; Heptamethylene difluoride
EINECS	Contact for details

Quality Control

Our 1,1-Difluorocycloheptane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including GC, NMR, and Karl Fischer titration to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed and upright to prevent leakage and concentration of vapors. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.0 g/mL
Boiling Point	~140-145°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.