Description

1-Chloromethyl-Isoquinoline is a versatile and reactive heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in the chloromethyl group, which provides a key handle for further functionalization, enabling the construction of complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive isoquinoline derivatives, including potential therapeutic agents for neurological and oncological targets.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the isoquinoline scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal complexation studies.
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis Building Block: Provides a critical reactive site for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis.

Basic Information

Product Name	1-Chloromethyl-Isoquinoline
CAS No.	27311-65-5
Molecular Formula	C₁₀H₈ClN
Molecular Weight	177.63 g/mol
Synonyms	Isoquinoline, 1-(chloromethyl)-; 1-(Chloromethyl)isoquinoline; (Isoquinolin-1-yl)methyl chloride; 1-Chloromethylisoquinoline; 1-Isoquinolinylmethyl Chloride; 27311-65-5; NSC 163082
EINECS	Contact for details

Quality Control

Our 1-Chloromethyl-Isoquinoline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.