Description

Indole-3-Propionic Acid, -α--Mercapto-, Dl- (8Ci) is a specialized sulfur-containing derivative of indole-3-propionic acid, featuring a mercapto group at the alpha position of the propionic acid side chain. This unique structure makes it a valuable advanced synthetic intermediate and a key building block for research into bioactive molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations due to its indole and thiol functionalities.
• Peptidomimetics & Prodrug Development: The mercapto and carboxylic acid groups make it a versatile scaffold for constructing peptide analogs and designing prodrugs.
• Agrochemical Synthesis: Employed in research for developing new plant growth regulators or protective agents.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with unique properties.

Basic Information

Product Name	Indole-3-Propionic Acid, -α--Mercapto-, Dl- (8Ci)
CAS No.	27266-99-5
Molecular Formula	C11H11NO2S
Molecular Weight	221.27 g/mol
Synonyms	DL-α-Mercapto-3-indolepropionic Acid; 3-(3-Indolyl)-2-mercaptopropionic Acid; (±)-2-Mercapto-3-(1H-indol-3-yl)propanoic Acid; 2-Sulfanyl-3-(1H-indol-3-yl)propanoic Acid; α-Mercaptotryptophan (carboxylated analog); 3-Indole-α-mercaptopropionic Acid; IPA-α-SH; 27266-99-5
EINECS	Contact for details

Quality Control

Our Indole-3-Propionic Acid, -α--Mercapto-, Dl- (8Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades and analytical documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.