Description

O o-Bis(2-Chloroethyl)Polyethylene Glyco is a specialized chlorinated polyethylene glycol derivative, functioning as a key bifunctional alkylating agent and a versatile chemical intermediate. Its primary value lies in its ability to introduce reactive chloroethyl groups, enabling the synthesis of complex molecules and functional materials. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and polymer industries seeking to create novel compounds or modify material properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of cytostatic agents and other therapeutic compounds.
• Polymer Modification: Acts as a cross-linking agent or a functional monomer to introduce reactive sites into polyethylene glycol (PEG) polymers, altering solubility, biocompatibility, or creating hydrogel networks.
• Agrochemical Synthesis: Serves as a building block for creating herbicides, pesticides, and plant growth regulators that require specific chlorinated ethylene glycol motifs.
• Chemical Research: A valuable reagent in organic synthesis for constructing complex molecular architectures, including crown ether analogs and dendrimers.
• Surface Functionalization: Used to modify surfaces of materials (e.g., nanoparticles, medical devices) with PEG chains to enhance hydrophilicity and reduce biofouling.
• Linker Chemistry: Employed in bioconjugation and the development of prodrugs, where its reactive end groups can attach to targeting molecules or masking groups.

Basic Information

Product Name	O o-Bis(2-Chloroethyl)Polyethylene Glyco
CAS No.	27252-69-3
Molecular Formula	C2n+4H4n+8Cl2On+1 (n = number of ethylene oxide units)
Molecular Weight	Varies by PEG chain length (n). Contact for details on specific grades.
Synonyms	α,ω-Bis(2-chloroethyl)poly(oxy-1,2-ethanediyl); Polyethylene glycol bis(2-chloroethyl) ether; PEG bis(2-chloroethyl) ether; Bis(2-chloroethyl) ether of polyethylene glycol; 2,2'-[1,2-ethanediylbis(oxy)]bis[chloroethane]; Chlorinated PEG; Dichloro-terminated polyethylene glycol
EINECS	Contact for details.

Quality Control

Our O o-Bis(2-Chloroethyl)Polyethylene Glyco is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Key parameters monitored include assay (by titration or NMR), residual solvents, and average molecular weight distribution. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions. Keep separated from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or waxy solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Average Molecular Weight (n)	As per customer grade (e.g., n=4, 9, 14, etc.)
Water Content (KF)	≤ 0.5%
Chloride Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.