Description

4-Pyridinepropanethiol is a specialized organosulfur compound featuring a pyridine ring linked to a propanethiol chain, making it a valuable heterocyclic building block. This compound matters for its unique reactivity profile, where the thiol group serves as a versatile handle for conjugation, metal chelation, and nucleophilic addition reactions, while the pyridine moiety can act as a ligand or participate in further heterocyclic chemistry. It is primarily needed by researchers and manufacturers in the pharmaceutical industry for developing active pharmaceutical ingredients (APIs), as well as in agrochemical synthesis and materials science for creating functional polymers and metal-organic frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Ligand Synthesis: Used to prepare chelating ligands for catalysis and metal ion extraction processes.
• Polymer Modification: Acts as a chain-transfer agent or functional monomer to introduce thiol groups into polymers for cross-linking or surface functionalization.
• Bioconjugation Reagent: Utilized for attaching small molecules, dyes, or drugs to proteins, antibodies, or nanoparticles via thiol-maleimide or disulfide chemistry.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Research & Development: Serves as a critical reagent in academic and industrial R&D for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	4-Pyridinepropanethiol
CAS No.	26847-63-2
Molecular Formula	C8H11NS
Molecular Weight	153.24 g/mol
Synonyms	4-(3-Mercaptopropyl)pyridine; 3-(4-Pyridyl)propanethiol; 4-Pyridylpropanethiol; 3-(Pyridin-4-yl)propane-1-thiol; 4-(3-Sulfanylpropyl)pyridine; Pyridine, 4-(3-mercaptopropyl)-; 26847-63-2
EINECS	Contact for details

Quality Control

Our 4-Pyridinepropanethiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and light-sensitive (store away from light), it is recommended to store the material under an inert gas atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Keep the container tightly sealed in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.