Description

(2S,4As,8As)-1,1,5,5-Tetramethylhexahydro-1H-2,4A-Methanonaphthalen-8(2H)-One is a high-purity, stereochemically defined synthetic intermediate of significant value in advanced organic synthesis. This compound matters for its role as a sophisticated building block in the production of complex molecules, particularly within the fragrance and pharmaceutical sectors. It is needed by R&D chemists and process development teams seeking a reliable, high-quality chiral precursor for creating novel compounds with specific olfactory or biological properties.

Application

• Fragrance & Flavor Industry: A key chiral intermediate for the synthesis of high-value amber, woody, and musky aroma chemicals.
• Pharmaceutical Research: Serves as a specialized building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Organic Synthesis: Used in academic and industrial research for constructing complex polycyclic frameworks and studying stereoselective reactions.
• Fine Chemical Production: Employed in the manufacture of other high-purity, specialty chemicals requiring a defined stereochemical backbone.

Basic Information

Product Name	(2S,4As,8As)-1,1,5,5-Tetramethylhexahydro-1H-2,4A-Methanonaphthalen-8(2H)-One
CAS No.	26839-51-0
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	Ambrox; Ambroxan; Ambroxide; (2S,4As,8As)-1,1,5,5-Tetramethylhexahydro-1H-2,4A-methanonaphthalen-8(2H)-one; (2S,4As,8As)-1,1,5,5-Tetramethyloctahydro-2,4A-methanonaphthalen-8(2H)-one; (-)-Ambrox; (8S,12S)-8,12-Epoxy-13,14,15,16-tetranorlabdane; Dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan
EINECS	Contact for details

Quality Control

Our (2S,4As,8As)-1,1,5,5-Tetramethylhexahydro-1H-2,4A-Methanonaphthalen-8(2H)-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral purity assessment by GC or HPLC, to meet the exacting standards required for fragrance and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Chiral Purity (GC)	≥ 99.0% (2S,4As,8As) isomer
Melting Point	75 - 80 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.