Description

3-Trimethylsiloxy-3-Butenoic Acid Trimethylsilyl Ester is a versatile organosilicon reagent featuring a silyl-protected enol and a silyl ester group. This dual functionality makes it a valuable synthetic building block for the controlled introduction of the 3-butenoic acid moiety under mild conditions. It is primarily utilized by pharmaceutical intermediates and fine chemical manufacturers for constructing complex molecules in advanced R&D and production.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functionalized butenoate chains.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides requiring specific carboxylic acid derivatives.
• Polymer & Material Science: Serves as a monomer or modifier in the development of specialty silicones and functional polymers.
• Organic Synthesis Reagent: Employed in academic and industrial research for palladium-catalyzed cross-coupling reactions and nucleophilic additions.
• Flavor & Fragrance Industry: Acts as a precursor for synthesizing specific ester compounds used in high-value aroma chemicals.
• Protecting Group Strategy: The trimethylsilyl groups provide temporary protection for carboxylic acid and enol functionalities during multi-step syntheses.

Basic Information

Item	Detail
Product Name	3-Trimethylsiloxy-3-Butenoic Acid Trimethylsilyl Ester
CAS No.	26802-51-7
Molecular Formula	C11H24O3Si2
Molecular Weight	260.48 g/mol
Synonyms	3-Butenoic acid, 3-(trimethylsiloxy)-, trimethylsilyl ester; Trimethylsilyl 3-(trimethylsiloxy)-3-butenoate; 3-(Trimethylsiloxy)-3-butenoic acid trimethylsilyl ester; 3-Trimethylsiloxybut-3-enoic acid trimethylsilyl ester; TMS enol ether of acetoacetic acid TMS ester (derivative); Bis(trimethylsilyl) acetoacetate enol ether; Acetoacetic acid bis(trimethylsilyl) enol ether
EINECS	Contact for details

Quality Control

Our production of 3-Trimethylsiloxy-3-Butenoic Acid Trimethylsilyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.