Description

1,2-Bis(Bromomethyl)-4,5-Dimethoxybenzene is a versatile and highly functionalized aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the reactivity of its bromomethyl groups, which serve as excellent handles for further molecular elaboration through nucleophilic substitution or cross-coupling reactions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring bridged or constrained structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the dimethoxybenzene scaffold is pharmacologically relevant.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Employed as a monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., Williamson ether synthesis, nucleophilic substitution) to introduce functionalized aromatic units.
• Research and Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	1,2-Bis(Bromomethyl)-4,5-Dimethoxybenzene
CAS No.	26726-81-8
Molecular Formula	C10H12Br2O2
Molecular Weight	324.01 g/mol
Synonyms	4,5-Dimethoxy-1,2-bis(bromomethyl)benzene; 1,2-Bis(bromomethyl)-4,5-dimethoxybenzene; 4,5-Dimethoxy-o-xylene-α,α'-dibromide; NSC 403796; 1,2-Di(bromomethyl)-4,5-dimethoxybenzene; 4,5-Dimethoxybenzene-1,2-dimethanediyl dibromide; o-Xylene, 4,5-dimethoxy-α,α'-dibromo-
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Bromomethyl)-4,5-Dimethoxybenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development, as well as cGMP standards for pharmaceutical intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.