Description

Dihydrovirginiamycin S1 CAS NO 26549-61-1 is a semi-synthetic derivative of the streptogramin antibiotic virginiamycin S1, characterized by its enhanced chemical stability. This compound is valued for its potent antibacterial activity, particularly against Gram-positive bacteria, and serves as a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel antimicrobial agents and the study of bacterial resistance mechanisms.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced streptogramin-class antibiotics.
• Antimicrobial Research: Used in microbiological and biochemical studies to investigate mechanisms of action against resistant bacterial strains.
• Veterinary Medicine Development: Serves as a reference standard or active component in research for animal health products targeting bacterial infections.
• Biochemical Assay Standard: Employed as a high-purity standard in HPLC or LC-MS methods for quality control and analytical method development.
• Mode of Action Studies: Utilized in research to study protein synthesis inhibition in bacteria at the ribosomal level.

Basic Information

Product Name	Dihydrovirginiamycin S1
CAS No.	26549-61-1
Molecular Formula	C43H49N7O10
Molecular Weight	823.90 g/mol
Synonyms	Dihydrovirginiamycin S; Virginiamycin S1 Dihydro Derivative; Antibiotic MA 144 S1 Dihydro; (3R,4R,5R,8R,11S,12S,13S,15AS)-13-[[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy]-3-ethyl-4,5,9,11,12,14,15,15a-octahydro-8,12-dihydroxy-3,5,8,10,14-pentamethyl-6H-oxepino[2,3-f]pyrido[1,2-a][1,5]diazacyclopentadecine-1,7,9-trione; Pristinamycin IIA Dihydro Derivative; Streptogramin B Derivative
EINECS	Contact for details

Quality Control

Our Dihydrovirginiamycin S1 is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to meet the stringent requirements of pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.