Description

Methyl 2-Dimethoxyphosphorylpropanoate is a high-purity organophosphorus compound, specifically a phosphonate ester, serving as a critical intermediate in advanced organic synthesis. Its value lies in its unique molecular structure, which provides a versatile platform for constructing complex molecules with precise stereochemistry and functional groups. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for active ingredient synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with phosphonate or phosphate ester functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators where the phosphonate moiety is crucial for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral or achiral phosphine-phosphonate ligands used in asymmetric catalysis and transition metal complexes.
• Peptide Mimetics & Prodrug Development: Employed in medicinal chemistry to create phosphonate-based bioisosteres and prodrugs to enhance drug stability, bioavailability, and targeting.
• Material Science Research: Utilized as a monomer or cross-linking agent in the development of specialty polymers and flame-retardant materials.
• Chemical Biology Probes: Acts as a scaffold for developing activity-based probes and inhibitors for studying enzyme mechanisms, particularly phosphatases and kinases.

Basic Information

Product Name	Methyl 2-Dimethoxyphosphorylpropanoate
CAS No.	26530-60-9
Molecular Formula	C6H13O5P
Molecular Weight	196.14 g/mol
Synonyms	Methyl 2-(Dimethoxyphosphoryl)propanoate; Dimethyl (1-Methoxy-1-oxopropan-2-yl)phosphonate; Methyl 2-(Dimethoxyphosphinyl)propionate; 2-(Dimethoxyphosphoryl)propionic Acid Methyl Ester; Methyl α-(Dimethoxyphosphoryl)propionate; Phosphonic acid, P-(1-methoxy-1-oxo-2-propanyl)-, dimethyl ester; (Methoxycarbonyl)ethyldimethylphosphonate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Dimethoxyphosphorylpropanoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO 9001 standards ensures a reliable supply of this high-value intermediate for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.