Description

1-(Triphenylphosphoranylidene)-3,3-Dimethyl-2-Butanone is a specialized Wittig reagent, a key organophosphorus compound used in synthetic organic chemistry. Its primary value lies in its ability to facilitate the synthesis of alkenes from carbonyl compounds, offering high selectivity and yield under mild conditions. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise olefination reactions to build complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing carbon-carbon double bonds in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Development: Used in the production of specialized pesticides, herbicides, and plant growth regulators requiring specific alkene functionalities.
• Advanced Material Precursors: Employed in the synthesis of organic ligands, liquid crystals, and polymers where controlled olefination is crucial for material properties.
• Academic & Industrial R&D: A staple in research laboratories for method development, total synthesis projects, and exploring new reaction pathways in organic chemistry.
• Fine Chemical Manufacturing: Applied in the multi-step synthesis of high-value, complex fragrance and flavor compounds.

Basic Information

Product Name	1-(Triphenylphosphoranylidene)-3,3-Dimethyl-2-Butanone
CAS No.	26487-93-4
Molecular Formula	C24H23OP
Molecular Weight	358.42 g/mol
Synonyms	3,3-Dimethyl-1-(triphenylphosphoranylidene)-2-butanone; Triphenyl(3,3-dimethyl-2-oxobutylidene)phosphorane; (3,3-Dimethyl-2-oxobutylidene)triphenylphosphorane; Wittig Reagent for Pinacolone; Pinacolone Ylide; 1-(Triphenylphosphonio)-3,3-dimethyl-2-oxobutylide
EINECS	Contact for details

Quality Control

Our production of 1-(Triphenylphosphoranylidene)-3,3-Dimethyl-2-Butanone adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by NMR/HPLC), identity confirmation, and moisture content. Our quality management system is designed to support cGMP and ISO standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent decomposition. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (NMR)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.