Description

3-Mercaptoisobutyric Acid is a versatile organosulfur compound featuring both a thiol and a carboxylic acid functional group. This bifunctional nature makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical and polymer industries. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), peptide mimetics, and specialty polymers requiring controlled cross-linking or specific functionalization.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing cysteine analogs, ACE inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the synthesis of modified peptides and peptide mimetics where the thiol group enables specific conjugation or cyclization.
• Polymer Modification & Cross-linking Agent: Serves as a chain transfer agent or cross-linker in the production of specialty polymers, including acrylic resins and adhesives.
• Chemical Synthesis: A versatile reagent for introducing the thiol functionality into target molecules in organic synthesis.
• Cosmetic Ingredients: Potential intermediate in the synthesis of certain hair waving or skin care actives.
• Research & Development: Valuable tool in biochemical and material science research for creating novel thiol-containing compounds.

Basic Information

Product Name	3-Mercaptoisobutyric Acid
CAS No.	26473-47-2
Molecular Formula	C4H8O2S
Molecular Weight	120.17 g/mol
Synonyms	3-Mercapto-2-methylpropanoic Acid; 2-Methyl-3-mercaptopropanoic Acid; β-Mercaptoisobutyric Acid; 3-Sulfanyl-2-methylpropanoic Acid; MIBA; 3-Thioisobutyric Acid; (RS)-3-Mercapto-2-methylpropionic Acid
EINECS	247-740-8

Quality Control

Our 3-Mercaptoisobutyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high standards required for pharmaceutical and industrial applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Gravity (20°C)	1.15 - 1.18
Refractive Index (20°C)	1.480 - 1.490

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.