Description

1,4-Naphthoquinone-D6 is a deuterated analog of 1,4-naphthoquinone, where six hydrogen atoms are replaced with the stable isotope deuterium. This high-purity labeled compound is essential for applications requiring precise internal standards and metabolic pathway tracing in advanced analytical research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on pharmacokinetics, drug metabolism, and environmental fate studies.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical reference standard in LC-MS and GC-MS methods for the accurate quantification of 1,4-naphthoquinone and related metabolites.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of pharmaceutical compounds in biological systems.
• Mechanistic Biochemical Research: Enables detailed investigation of enzymatic reactions and metabolic pathways involving quinone structures without interference from protonated species.
• Environmental Analysis: Acts as a labeled standard for detecting and quantifying naphthoquinone derivatives in complex environmental samples.
• Stable Isotope Labeling: Provides a non-radioactive tool for tracking molecular fate in chemical and biological processes.

Basic Information

Product Name	1,4-Naphthoquinone-D6
CAS No.	26473-08-5
Molecular Formula	C10D6O2
Molecular Weight	174.20 g/mol
Synonyms	1,4-Naphthalenedione-D6; 1,4-Naphthoquinone (hexadeuterated); Naphthoquinone-D6; p-Naphthoquinone-D6; 5,6,7,8-Tetradeutero-1,4-naphthoquinone; α-Naphthoquinone-D6; Deuteronaphthoquinone; [D6]-1,4-Naphthoquinone
EINECS	Contact for details

Quality Control

Our 1,4-Naphthoquinone-D6 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is characterized by NMR and mass spectrometry to confirm deuteration level and chemical purity. Certificates of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity (by HPLC), and analytical data are provided to guarantee traceability and consistency for your research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % D)	≥98%
Chemical Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.