Description

1-Azabicyclo[2.2.2]octan-4-ol is a versatile bicyclic tertiary amine alcohol, serving as a crucial advanced pharmaceutical intermediate and a valuable scaffold in organic synthesis. Its rigid, three-dimensional structure makes it an essential building block for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its role in creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of muscarinic receptor antagonists and other neurologically active compounds.
• Chiral Building Block: Used in asymmetric synthesis to introduce stereochemical complexity into target molecules.
• Ligand Synthesis: Serves as a backbone for creating complex ligands in catalysis and medicinal chemistry.
• Agrochemical Research: Intermediate in the development of new crop protection agents and herbicides.
• Academic & R&D: A valuable tool for methodological development and exploring new chemical space in organic chemistry laboratories.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals for various high-value applications.

Basic Information

Product Name	1-Azabicyclo[2.2.2]octan-4-ol
CAS No.	26458-74-2
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	4-Hydroxyquinuclidine; Quinuclidin-4-ol; 1-Azabicyclo[2.2.2]octan-4-ol; 4-Quinuclidinol; 3-Quinuclidinol (common misnomer); 1-Azabicyclo(2.2.2)octan-4-ol; 4-Hydroxy-1-azabicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]octan-4-ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and manufacturing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.