Description

Dehydroheliotridine is a pyrrolizidine alkaloid derivative of significant interest in biochemical and pharmacological research. This compound serves as a crucial intermediate and reference standard for studying the metabolism, toxicity, and biological activity of pyrrolizidine alkaloids. It is primarily utilized by research institutions, pharmaceutical development laboratories, and chemical manufacturers focused on natural product chemistry and toxicology. The product is supplied with a commitment to high purity and batch-to-batch consistency for reliable experimental results.

Application

• Pharmaceutical Research: Used as a key intermediate or metabolite standard in the study of pyrrolizidine alkaloid toxicity, hepatotoxicity mechanisms, and metabolic pathways.
• Biochemical Analysis: Serves as an analytical reference standard for the identification and quantification of related alkaloids in complex matrices via HPLC, LC-MS, or GC-MS.
• Toxicology Studies: Employed in in vitro and in vivo models to investigate the genotoxic and cytotoxic effects of dehydropyrrolizidine alkaloids.
• Natural Product Chemistry: Acts as a synthetic building block or a comparative standard in the isolation, characterization, and synthesis of pyrrolizidine alkaloids from plant sources.
• Quality Control & Safety Testing: Used by manufacturers of herbal supplements, teas, and food products to screen for and quantify potentially harmful pyrrolizidine alkaloid contaminants.
• Academic Research: Fundamental research tool in universities and institutes for exploring the chemistry, biosynthesis, and environmental impact of these natural products.

Basic Information

Item	Detail
Product Name	Dehydroheliotridine
CAS No.	26400-24-8
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	1,2-Dehydroheliotridine; (E)-7-Hydroxy-1-methyl-1,2-dehydropyrrolizidin-3-one; Dehydroheliotridin; 7-Hydroxy-1-methyl-1,2-dehydro-8H-pyrrolizidin-3-one; 1-Methyl-1,2-dehydro-7-hydroxypyrrolizidin-3-one; Otonecine base; Dehydroheliotridine alkaloid
EINECS	Contact for details

Quality Control

Our Dehydroheliotridine is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by chromatographic techniques (HPLC). We provide a detailed Certificate of Analysis (COA) with each shipment, documenting the assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.