Description

[(6-Iodohexyl)Oxy]Trimethylsilane is a versatile organosilicon compound featuring a reactive iodoalkyl chain and a silyl ether protecting group. This bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules and functional materials. It is particularly sought after by researchers and manufacturers in the pharmaceutical, materials science, and specialty chemical industries for applications requiring controlled molecular assembly and surface modification.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where the iodo group serves as a handle for further functionalization.
• Surface Modification Agent: Employed to functionalize silica, glass, and other oxide surfaces, creating hydrophobic or reactive coatings for chromatography, sensors, and advanced composites.
• Polymer & Dendrimer Synthesis: Acts as a key building block (monomer or cross-linker) in the preparation of specialty polymers, dendrimers, and liquid crystals.
• Organic Synthesis Reagent: Serves as a protected hydroxyalkyl iodide equivalent in multi-step organic synthesis, enabling the introduction of elongated carbon chains.
• Bioconjugation Linker: Utilized to attach biomolecules (e.g., peptides, sugars) to surfaces or other molecules via the reactive iodo functionality.
• Material Science Research: Applied in the development of self-assembled monolayers (SAMs) and organic-inorganic hybrid materials.

Basic Information

Product Name	[(6-Iodohexyl)Oxy]Trimethylsilane
CAS No.	26306-01-4
Molecular Formula	C9H21IOSi
Molecular Weight	300.26 g/mol
Synonyms	6-(Trimethylsilyloxy)hexyl Iodide; 1-Iodo-6-(trimethylsilyloxy)hexane; Trimethyl(6-iodohexyloxy)silane; (6-Iodohexyloxy)trimethylsilane; Hexyl iodide, 6-(trimethylsilyloxy)-; Iodohexyloxytrimethylsilane; O-[(6-Iodohexyl)]trimethylsilanol; TMS-protected 6-iodo-1-hexanol
EINECS	Contact for details

Quality Control

Our [(6-Iodohexyl)Oxy]Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.