Description

2,6-Difluoro-3-Methylbenzyl Alcohol is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. Its structure, featuring both a benzyl alcohol moiety and strategically placed fluorine atoms, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its fluorine atoms can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for active pharmaceutical ingredients (APIs) requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoromethylbenzyl structure can contribute to efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Functional Material Development: Employed in creating specialty polymers, coatings, and electronic chemicals that benefit from the introduction of fluorine.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, etherifications, and esterifications to introduce the 2,6-difluoro-3-methylbenzyl group into more complex architectures.

Basic Information

Product Name	2,6-Difluoro-3-Methylbenzyl Alcohol
CAS No.	26173-40-0
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(2,6-Difluoro-3-methylphenyl)methanol; 2,6-Difluoro-3-methylbenzenemethanol; 3-(Hydroxymethyl)-2,6-difluorotoluene; 2,6-Difluoro-3-methyl-benzylalcohol; α,2,6-Trifluoro-m-tolyl alcohol; 26173-40-0; 2,6-Difluoro-m-tolylcarbinol
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methylbenzyl Alcohol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures a reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.