Description

[[2S,3R,(+)]-3-Methyloxiran-2-Yl]Phosphonic Acid is a high-purity, chiral organophosphorus compound featuring a reactive epoxide ring, making it a valuable building block for stereoselective synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in advanced chemical synthesis. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and specialty materials where its defined stereochemistry and functional groups enable the creation of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and enzyme inhibitor drug candidates.
• Agrochemical Synthesis: Used in the development of novel, stereospecific herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral phosphonate ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation and Probe Chemistry: The reactive epoxide allows for selective modification of proteins, peptides, and other biomolecules for research and diagnostic applications.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced materials with specific surface properties or reactivity.
• Chemical Biology Tool: Acts as an irreversible inhibitor or activity-based probe for studying enzyme mechanisms and function.

Basic Information

Product Name	[[2S,3R,(+)]-3-Methyloxiran-2-Yl]Phosphonic Acid
CAS No.	26017-03-8
Molecular Formula	C4H9O4P
Molecular Weight	152.09 g/mol
Synonyms	(2S,3R)-3-Methyloxiran-2-ylphosphonic Acid; (+)-(2S,3R)-3-Methyl-2-oxiranylphosphonic Acid; (2S,3R)-Epoxybutylphosphonic Acid; Fosfomycin Intermediate; (2S,3R)-1,2-Epoxypropylphosphonic Acid; PEPA (in specific research contexts); L-(-)-cis-1,2-Epoxypropylphosphonic Acid (related isomer).
EINECS	Contact for details

Quality Control

Our [[2S,3R,(+)]-3-Methyloxiran-2-Yl]Phosphonic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.