Description

1-[[(Chloromethyl)Dimethylsilyl]Ethynyl]-1-Cyclohexanol is a specialized organosilicon compound that serves as a versatile building block in advanced organic synthesis. Its unique molecular architecture, featuring both a silyl-protected alkyne and a cyclohexanol moiety, makes it a critical intermediate for constructing complex molecular frameworks. This high-value chemical is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as medicinal chemistry and polymer cross-linking.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting complex bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its functional groups for structural diversification.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty silicones, resins, and functional polymers.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules via silicon-assisted transformations and click chemistry.
• Surface Modification Agent: Utilized to introduce specific functional groups onto material surfaces for enhanced properties like adhesion or hydrophobicity.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Item	Details
Product Name	1-[[(Chloromethyl)Dimethylsilyl]Ethynyl]-1-Cyclohexanol
CAS No.	25911-25-5
Molecular Formula	C11H19ClOSi
Molecular Weight	230.80 g/mol
Synonyms	1-[(Chloromethyl)dimethylsilyl]ethynyl-1-cyclohexanol; (Chloromethyl)dimethyl(1-hydroxy-1-cyclohexylethynyl)silane; 1-Cyclohexanol, 1-[[(chloromethyl)dimethylsilyl]ethynyl]-; 1-(2-((Chloromethyl)dimethylsilyl)ethynyl)cyclohexan-1-ol; (1-Hydroxycyclohexyl)ethynyl(chloromethyl)dimethylsilane; DMSE-CH; TMS-protected alkyne alcohol derivative
EINECS	Contact for details

Quality Control

Our production of 1-[[(Chloromethyl)Dimethylsilyl]Ethynyl]-1-Cyclohexanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.