Description

Potassium Cyanoborodeuteride is a specialized deuterated reagent, a key isotopically labeled variant of potassium cyanoborohydride. This compound is essential for researchers and manufacturers requiring precise deuterium labeling in synthetic pathways, offering unique advantages in reaction mechanisms and analytical studies. It is primarily utilized in advanced pharmaceutical research, organic synthesis, and as a critical tool in spectroscopic analysis and kinetic isotope effect studies.

Application

• Deuterium Labeling in Pharmaceutical Intermediates: Used for the site-specific incorporation of deuterium atoms into drug molecules and active pharmaceutical ingredients (APIs) for metabolic stability studies.
• Selective Reductive Amination: Acts as a mild and selective reducing agent for reductive amination reactions in deuterated solvent systems or for producing deuterium-labeled amines.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a deuterium source for preparing isotopically labeled compounds used as internal standards or for complex structural elucidation.
• Mechanistic Studies in Organic Chemistry: Employed in kinetic isotope effect (KIE) experiments to investigate reaction mechanisms and pathways.
• Deuterium Exchange Reactions: Facilitates specific hydrogen-deuterium exchange processes in complex organic molecules.
• Synthesis of Deuterated Fine Chemicals: Key reagent for producing deuterium-labeled fine chemicals, flavors, and fragrances for research and development.

Basic Information

Product Name	Potassium Cyanoborodeuteride
CAS No.	25895-63-0
Molecular Formula	CH2BD2KN
Molecular Weight	83.98 g/mol (approx.)
Synonyms	Potassium (cyano-2H2)boranuide; Potassium Cyanoborodideuteride; Potassium Deuterated Cyanoborohydride; Potassium (Cyanotrihydroborato(2-))dideuterium; Deuterated Potassium Cyanoborohydride; KBH(CN)D2; Potassium (Cyanodideuterioboranuide); Potassium Cyanoborohydride-d2
EINECS	Contact for details

Quality Control

Our Potassium Cyanoborodeuteride is produced and handled under strict quality protocols to ensure high isotopic purity and chemical integrity, critical for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Deuterium Content (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.