Description

Sodium Cyanoborohydride is a versatile and highly selective reducing agent, widely recognized for its stability and effectiveness in aqueous and protic media. Its primary commercial value lies in its ability to perform reductive amination reactions under mild conditions, making it indispensable for complex organic synthesis. This compound is a critical reagent for pharmaceutical R&D, fine chemical manufacturing, and biochemical applications where precise and selective reduction is required.

Application

• Pharmaceutical Synthesis: A key reagent for the reductive amination of aldehydes and ketones in the production of active pharmaceutical ingredients (APIs).
• Bioconjugation & Protein Chemistry: Used for the selective reduction of Schiff bases in antibody-drug conjugate (ADC) development and protein labeling.
• Carbohydrate Chemistry: Employed in the synthesis of glycosylamines and other complex sugar derivatives.
• Fine Chemical Manufacturing: Facilitates the synthesis of specialty amines, agrochemical intermediates, and dyes.
• Polymer Modification: Used to introduce amine functionalities or cross-link polymers under controlled conditions.
• Analytical Chemistry: Acts as a derivatization agent in chromatographic analysis and sample preparation.

Basic Information

Product Name	Sodium Cyanoborohydride
CAS No.	25895-60-7
Molecular Formula	NaBH3CN
Molecular Weight	62.84 g/mol
Synonyms	Sodium Cyanotrihydroborate; Sodium Borocyanohydride; Cyanotrihydroborate Sodium Salt; Sodium Hydrogen Cyanoboranuide; NaBH3CN; Sodium Cyanoboranuide; Sodium Trihydrocyanoboranuide
EINECS	247-317-7

Quality Control

Our Sodium Cyanoborohydride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay, impurity profiling, and moisture content determination. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (NaBH3CN)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.