Description

(S)-(+)-1-Phenyl-1,2-Ethanediol is a high-purity chiral diol building block of significant importance in asymmetric synthesis. Its enantiomeric purity makes it a valuable intermediate for the production of pharmaceuticals, agrochemicals, and fine chemicals. This compound is particularly sought after by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of various APIs, including β-blockers, antidepressants, and antiviral agents.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Intermediate in the manufacture of flavors, fragrances, and advanced materials requiring specific stereochemistry.
• Academic & Industrial Research: A standard reagent in methodological development for stereoselective reactions like dihydroxylation and kinetic resolution.

Basic Information

Product Name	(S)-(+)-1-Phenyl-1,2-Ethanediol
CAS No.	25779-13-9
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	(S)-(+)-1-Phenylethane-1,2-diol; (S)-(+)-1-Phenylethylene Glycol; (S)-(+)-Styrene Glycol; (S)-(+)-Mandelic Alcohol; (S)-1-Phenyl-1,2-ethanediol; (S)-1-Phenyl-2-hydroxyethanol; (S)-Phenylglycol; (S)-Styrene Glycol; L-1-Phenyl-1,2-ethanediol
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-Phenyl-1,2-Ethanediol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	65 - 68 °C
Specific Rotation [α]20/D	+40° to +44° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.