Description

1,2-Dipalmitoyl-D62-Sn-Glycero-3-Phosphocholine is a deuterated, high-purity phospholipid, specifically a perdeuterated analog of DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine). This compound is essential for advanced research applications where isotopic labeling is required to eliminate background interference and enable precise structural and dynamic analysis. It is primarily utilized by researchers and developers in the fields of biophysics, structural biology, and pharmaceutical formulation.

Application

• Biophysical Research: As a deuterated lipid for neutron scattering and diffraction studies to investigate model membrane structure and dynamics.
• NMR Spectroscopy: Used in solid-state and solution NMR to study lipid bilayer properties, protein-lipid interactions, and membrane protein structure without proton background.
• Liposome & Drug Delivery: A key component in the development of deuterated liposomal carriers for controlled release and targeted drug delivery systems.
• Membrane Protein Reconstitution: Facilitates the study of integral membrane proteins in a native-like, deuterated lipid environment.
• Surface Science: Used to create deuterated lipid monolayers and bilayers for studies with techniques like vibrational sum-frequency generation (VSFG) spectroscopy.
• Analytical Standards: Serves as a high-purity internal standard or reference material in mass spectrometry-based lipidomics.

Basic Information

Product Name	1,2-Dipalmitoyl-D62-Sn-Glycero-3-Phosphocholine
CAS No.	25582-63-2
Molecular Formula	C40D62NO8P
Molecular Weight	~734.0 g/mol (deuterated form)
Synonyms	DPPC-d62; 1,2-Dihexadecanoyl-D62-sn-glycero-3-phosphocholine; Perdeuterated DPPC; Deuterated Dipalmitoylphosphatidylcholine; DPPC (d62); 1,2-Dipalmitoylphosphatidylcholine-d62; L-α-Phosphatidylcholine, dipalmitoyl-D62; (2R)-2,3-Bis(hexadecanoyloxy)propyl (2-trimethylammonioethyl) phosphate-d62
EINECS	Contact for details

Quality Control

Our deuterated phospholipids are produced under stringent conditions to ensure the highest isotopic and chemical purity for sensitive research applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry to confirm deuteration level, chemical identity, and purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98 atom % D), chemical purity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Deuteration Degree	>98 atom % D
Purity (HPLC)	>95%
Solubility	Soluble in chloroform, methanol; forms liposomes in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.