Description

(S)-(+)-1-Indanol CAS NO 25501-32-0 is a high-purity, single-enantiomer chiral building block and intermediate of significant importance in asymmetric synthesis. Its rigid, fused-ring structure and defined stereochemistry make it a valuable scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), advanced materials, and specialty catalysts.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potent drug candidates, including enzyme inhibitors and receptor modulators.
• Asymmetric Catalysis Ligand: Used to develop and synthesize novel chiral ligands and organocatalysts for enantioselective transformations.
• Advanced Material Synthesis: Serves as a building block for creating chiral polymers, liquid crystals, and functional organic materials.
• Agrochemical Research: Employed in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing chiral odorants and flavor compounds with specific sensory profiles.
• Academic & Process R&D: A valuable tool for methodological studies in organic synthesis and scaling up chiral processes.

Basic Information

Product Name	(S)-(+)-1-Indanol
CAS No.	25501-32-0
Molecular Formula	C9H10O
Molecular Weight	134.18 g/mol
Synonyms	(S)-(+)-1-Indanol; (S)-1-Indanol; (S)-1-Indan-1-ol; (S)-Indan-1-ol; (+)-(S)-1-Hydroxyindane; (S)-1-Hydroxyindane; (S)-Indanol; (1S)-2,3-Dihydro-1H-inden-1-ol
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-Indanol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	52 - 56 °C
Specific Rotation [α]D20	+40.0° to +44.0° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.