Description

3-(1-Mercaptoethyl)-4,5-Dihydro-1H-1,2,4-Triazole-5-Thione is a specialized organosulfur compound featuring both a mercaptoethyl side chain and a triazolethione core, making it a versatile building block and intermediate. This compound matters for its unique reactivity profile, offering sites for nucleophilic substitution and metal complexation, which is critical for synthesizing advanced materials and active pharmaceutical ingredients. Industries that require high-purity heterocyclic intermediates, such as pharmaceutical research, agrochemical development, and specialty polymer chemistry, are the primary users of this chemical.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those with sulfur-containing heterocycles for therapeutic applications.
• Agrochemical Synthesis: Used in the development of new fungicides, herbicides, and plant growth regulators due to its bioactive triazole-thione structure.
• Corrosion Inhibitor Formulation: Acts as an effective component in coatings and additives for metal surface protection, leveraging its sulfur atoms to form protective layers.
• Polymer Additive & Cross-linking Agent: Employed in the production of specialty polymers and rubbers to enhance thermal stability, elasticity, and cross-link density.
• Chemical Research & Development: A valuable reagent for exploring new organic reactions, ligand synthesis for catalysis, and material science applications.
• Analytical Chemistry: Can be used as a chelating agent or a derivatization reagent in analytical methods for metal ion detection.

Basic Information

Product Name	3-(1-Mercaptoethyl)-4,5-Dihydro-1H-1,2,4-Triazole-5-Thione
CAS No.	25366-56-7
Molecular Formula	C4H7N3S2
Molecular Weight	161.25 g/mol
Synonyms	1,2,4-Triazole-3-thiol, 4,5-dihydro-3-(1-mercaptoethyl)-; 3-(1-Mercaptoethyl)-1,2,4-triazoline-5-thione; 3-(2-Mercaptoethyl)-4H-1,2,4-triazole-5-thiol; 5-Mercapto-3-(2-mercaptoethyl)-1,2,4-triazole; 1,2,4-Triazoline-5-thione, 3-(2-mercaptoethyl)-; NSC 163031; 3-(β-Mercaptoethyl)-4,5-dihydro-1H-1,2,4-triazole-5-thione
EINECS	Contact for details

Quality Control

Our 3-(1-Mercaptoethyl)-4,5-Dihydro-1H-1,2,4-Triazole-5-Thione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.