Description

2-(Methyl-D3)Bromobenzene is a deuterium-labeled isotopologue of 2-bromotoluene, where three hydrogen atoms on the methyl group are replaced with deuterium. This precise isotopic labeling is critical for applications requiring non-radioactive tracers, internal standards, and mechanistic studies where metabolic pathways must be distinguished. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high chemical purity and isotopic enrichment for analytical and synthetic precision.

Application

• Pharmaceutical Research & Development: Serves as a stable isotope-labeled internal standard for the accurate quantification of metabolites and active pharmaceutical ingredients (APIs) in LC-MS and GC-MS analysis.
• Metabolic Pathway Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of molecules without the complexities of radioactive labeling.
• Organic Synthesis Intermediate: Acts as a key deuterated synthon for the preparation of more complex labeled compounds in medicinal chemistry and material science.
• Agrochemical Development: Employed in the synthesis and analysis of deuterated pesticides and herbicides to study environmental degradation and residue analysis.
• NMR Spectroscopy Solvent & Reagent: Useful as a probe or shifting agent in nuclear magnetic resonance (NMR) spectroscopy due to its distinct deuterium signature.
• Academic & Industrial Research: Fundamental reagent for mechanistic studies in organic chemistry, catalysis, and reaction kinetics.

Basic Information

Product Name	2-(Methyl-D3)Bromobenzene
CAS No.	25319-52-2
Molecular Formula	C7H4D3Br
Molecular Weight	174.04 g/mol
Synonyms	2-Bromo-1-(trideuteriomethyl)benzene; 2-Bromotoluene-d3; (2-Bromophenyl)(2H3)methane; 1-Bromo-2-(methyl-d3)benzene; o-Bromotoluene-d3; 2-Methyl-d3 Bromobenzene; Deutero-o-bromotoluene; 2-Bromo-α,α,α-trideuteriotoluene
EINECS	Contact for details

Quality Control

Our 2-(Methyl-D3)Bromobenzene is manufactured under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and industrial applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D-enrichment), chemical purity by GC/HPLC, and identity confirmation by NMR and IR spectroscopy. We adhere to a quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.